Publications

Latest publication 03/26/2022

Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skelet

Skeletal muscle atrophy is caused by aging, disuse, malnutrition, and several diseases. However, there are still no effective drugs or treatments...

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    [title] => Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skelet
    [paragraph] => Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skeletal Muscle Atrophy via Regulating the PI3K and Akt and SIRT1 and PGC-1alpha Pathways
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Authors
TY Kim, KT Park, SY Choung


Lab
Kyung Hee University, Seoul, Republic of Korea.

Journal
Phytomedicine

Abstract
Skeletal muscle atrophy is caused by aging, disuse, malnutrition, and several diseases. However, there are still no effective drugs or treatments for muscle atrophy. Codonopsis lanceolata (CL), a traditional medicinal plant and food, has been reported to have anti-oxidative, anti-inflammatory, anti-tumor, and anti-obesity effects. This study aimed to investigate the efficacy and active component of CL on muscle atrophy in vitro and to confirm the effect of CL and its active component on muscle atrophy and the underlying molecular mechanisms in vivo.

BIOSEB Instruments Used
Grip strength test (BIO-GS3)

Keywords/Topics
Muscular atrophy [meta_description] => [meta_keywords] => https://doi.org/10.1016/j.phymed.2022.154058 [meta_title] => [link_rewrite] => codonopsis-lanceolata-and-its-active-component-tangshenoside-i-ameliorate-skeletal-muscle-atrophy-via-regulating-the-pi3k-and-akt-and-sirt1-and-pgc-1alpha-pathways [actif_langue] => 1 [read] => 1331 [count_comments] => 0 [id] => 1522 [categories] => Array ( [65] => Array ( [id_prestablog_categorie] => 65 [title] => Muscular atrophy [link_rewrite] => atrophie ) [2] => Array ( [id_prestablog_categorie] => 2 [title] => Publications [link_rewrite] => publications ) ) [authors] => [paragraph_crop] => Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skeletal Muscle [...] [link_for_unique] => 1 [products_liaison] => Array ( [48] => Array ( [name] => Grip strength test [description_short] =>

An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.

New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)

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