Publications

Latest publication 12/01/2024

Deficiency of muscle-generated brain-derived neurotrophic factor causes inflamma

Idiopathic inflammatory myopathy (commonly known as myositis) is a group of immune-related diseases characterized by muscle damage, weakness, and fati

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    [title] => Deficiency of muscle-generated brain-derived neurotrophic factor causes inflamma
    [paragraph] => Deficiency of muscle-generated brain-derived neurotrophic factor causes inflammatory myopathy through reactive oxygen species-mediated necroptosis and pyroptosis
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Authors
Brian Pak Shing Pang, Elsie Chit Yu Iu, Miaojia Hang, Wing Suen Chan, Margaret Chui Ling Tse, Connie Tsz Ying Yeung, Mingfu Wang, Parco Ming Fai Siu, Chi Wai Lee, Keqiang Ye, Ho So, Chi Bun Chan

 Lab

Journal
Redox Biology
Abstract
Idiopathic inflammatory myopathy (commonly known as myositis) is a group of immune-related diseases characterized by muscle damage, weakness, and fati
Keywords/Topics
 BDNF;Muscle;ROS;Necroptosis;Pyroptosis
BIOSEB Instruments Used:
Grip strength test (BIO-GS4)
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An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.
New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)

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