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Latest publication 05/18/2024

DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 defic

GBA1 mutations are the most common genetic risk factor for development of Parkinson's disease (PD). The loss of catalytic activity in GBA1, as well a

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    [title] => DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 defic
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Authors
Nam, Younwoo, Na, Jiyeon, Ma, Shi-Xun, Park, Haeun, Park, Hyeonwoo, Lee, Eunmin, Kim, Hyerynn, Jang, Sang-Min, Ko, Han Seok, Kim, Sangjune



 Lab


Journal
Genes & Genomics


Abstract
GBA1 mutations are the most common genetic risk factor for development of Parkinson's disease (PD). The loss of catalytic activity in GBA1, as well a


Keywords/Topics
GBA1 deficiency ;Parkinson's disease; DJ - 1 Oxidative stress
BIOSEB Instruments Used:
Grip strength test (BIO-GS4)

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An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.


New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)


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