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Latest publication 05/11/2021

Capsazepine decreases corneal pain syndrome in severe dry eye disease

Dry eye disease (DED) is a multifactorial disease of the ocular surface accompanied by neurosensory abnormalities. Here, we evaluated the...

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    [title] => Capsazepine decreases corneal pain syndrome in severe dry eye disease
    [paragraph] => Capsazepine decreases corneal pain syndrome in severe dry eye disease
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Authors
D Fakih, A Guerrero-Moreno, C Baudouin



 Lab
Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012, Paris, France


Journal
Journal of Neuroinflammation


Abstract
Dry eye disease (DED) is a multifactorial disease of the ocular surface accompanied by neurosensory abnormalities. Here, we evaluated the effectiveness of transient receptor potential vanilloid-1 (TRPV1) blockade to alleviate ocular pain, neuroinflammation, and anxiety-like behavior associated with severe DED.
BIOSEB Instruments Used
Elevated Plus Maze : EPM3C - 3 clicks only ! (BIO-EPM3C)

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NEW ! A complete (hardware + software), dedicated and automated solution for the Elevated Plus Maze test, featuring unprecedented simplicity to run these very popular protocols. A user-friendly and innovative solution for your research on anxiety, depression and the screening of anxiolytic drugs.

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