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Latest publication 06/01/2026

TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sc

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron degeneration and cytoplasmic...

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    [title] => TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sc
    [paragraph] => TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis
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Authors
Barone, Cassandra, Wang, Rihua, Cooke, Sarah, Ng, Hang Pong, Ferreira, Rodolfo S., Miranda, Helen C., Qi, Xin



 Lab


Journal
Acta Neuropathologica


Abstract
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron degeneration and cytoplasmic mislocaliz


Keywords/Topics
Motor neuron; Metabolism; Glucose; Spinal cord
BIOSEB Instruments Used:
Grip strength test (BIO-GS4)

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An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.


New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)


forrats.pngformice.png

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